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Feb. 18, 2022 — Will springtime be booster time — once more?
The primary COVID-19 booster shot is now within the rearview mirror for hundreds of thousands of Individuals — for the 28% who obtained it, at the very least — however new information finds it’s much less efficient after about 4 months. The CDC has already really helpful a second booster for immunocompromised individuals.
So, is the following logical step one other booster for each different grownup?
The consensus amongst public well being officers appears to be: Not so quick.
On the White Home COVID-19 briefing Wednesday, chief White Home medical adviser Anthony Fauci, MD, centered on the query of the hour. Citing information, he mentioned that ”a single booster shot continues to offer high-level safety in opposition to extreme illness attributable to Omicron” in people who find themselves not immunocompromised.
Fauci pointed to CDC analysis that discovered vaccine effectiveness after two doses of mRNA vaccines — both Moderna or Pfizer — drops to 58% after 4-5 months. After a booster dose, the vaccine is 91% efficient, at first, at stopping hospitalizations. However that drops to 78% at months 4 to five. “Nonetheless, the extent of 78 [%] remains to be a very good protecting space,” Fauci mentioned.
“The long run requirement for a further increase, or a fourth shot for mRNA or a 3rd shot for [Johnson & Johnson], is being very fastidiously monitored in actual time,” he mentioned, including that suggestions shall be up to date as wanted.
Wait on the Knowledge
Different public well being officers and companies echo Fauci’s recommendation: Wait on the info.
“Right now, CDC doesn’t have a suggestion for a fourth dose/second booster dose for many Individuals,” says Scott Pauley, a CDC spokesperson.
In a preprint examine, which has not been peer-reviewed, launched this this week, researchers from Sheba Medical Middle in Israel adopted 274 well being care employees after a fourth dose of both the Moderna or the Pfizer vaccine. They discovered the second booster restored antibody ranges to the identical peak ranges after the third dose however was not good at stopping gentle or asymptomatic Omicron infections.
Breakthrough infections have been frequent. The researchers mentioned their outcomes recommend the necessity for ”next-generation vaccine growth.”
Contemplating the Pandemic’s Path
Selections about second booster pictures demand that we have a look at the large image, says William Schaffner, MD, an infectious illness specialist at Vanderbilt College Medical Middle in Nashville. In the meanwhile, he says, hospitalizations are down, and ”even deaths, a lagging indicator,” are declining, though to not the identical diploma in all elements of the nation. Even so, he says, the traits are moving into the precise path.
On the White Home briefing Wednesday, CDC director Rochelle Walensky, MD, mentioned federal officers are ”cautiously optimistic in regards to the trajectory we’re on,” noting that the present 7-day every day common of circumstances is about 147,000, down about 40% from the earlier week. Hospital admissions, at 9,500 a day, have declined about 28%, and the 7-day common of every day deaths is about 2,200, a lower of about 9% from the prior week.
The hope, Schaffner says, is that this mixture of the Omicron unfold, with many gaining pure immunity from that an infection, together with vaccination, will produce a sustained drop in circumstances. “If that’s the case, we do not want a booster anytime quickly.”
However that state of affairs additionally assumes we do not see a brand new variant of concern, he says.
Then, ”as we transfer from pandemic to endemic, we will decide at what interval a booster shall be vital and what the composition [of it] shall be,” Schaffner says. However for now, “I do not assume a fourth dose — a second booster — is within the playing cards within the near-term future [for those not immunocompromised], if the whole lot goes the best way it has been going.”
”What you may’t see is that each one my fingers are crossed,” he says.
Booster Objectives
It is arduous to provide ultimate solutions about boosters for the final inhabitants with out enough information but, agrees Alejandro Balazs, PhD, a virologist and principal investigator on the Ragon Institute of Massachusetts Normal Hospital, MIT, and Harvard.
The vital query: “Are we attempting to cease transmission or simply extreme illness?”
Amesh Adalja, MD, an infectious illness knowledgeable and senior scholar on the Johns Hopkins Middle for Well being Safety, agrees: “If the purpose is safety in opposition to severe illness, hospitalization, and dying, focusing on the boosting of high-risk populations [but not others] is sensible as the usual regimens are holding up within the normal inhabitants.”
At the same time as antibody ranges decline after vaccinations, your reminiscence T-cell and B-cell response might endure, making it potential to struggle the virus, Balazs says. “The antibodies can stop the an infection from establishing itself.”
Increase Now, Knowledge Later?
Regardless of the dearth of information, medical doctors say their sufferers are asking now about second boosters.
“At this cut-off date, it’s inconceivable to foretell whether or not extra booster doses shall be wanted for wholesome individuals,” says Aaron Glatt, MD, chief of infectious ailments at Mount Sinai South Nassau in Oceanside, NY.
Might untimely boosting by wholesome individuals have a draw back? “I do not see any quick hurt [to that]. Nonetheless, I am not so positive in regards to the profit,” Schaffner says.
“The one hurt is hypothetical,” Adalja says, “and it’s that persevering with to spice up with first-generation vaccines directed in opposition to the ancestral pressure of the virus might blunt the flexibility of the immune system to completely reply to new variants.”
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openx.com,539154393,RESELLER
tremorhub.com,z87wm,RESELLER,1a4e959a1b50034a
rubiconproject.com,16698,RESELLER,0bfd66d529a55807
freewheel.tv,799841,RESELLER
freewheel.tv,799921,RESELLER
aol.com,53392,RESELLER
rhythmone.com,1166984029,RESELLER,a670c89d4a324e47
richaudience.com,mA6M9Pbvib,DIRECT
adform.com,1942,DIRECT
adform.com,1941,DIRECT
advertising.com,7574,DIRECT
aerserv.com,2750,RESELLER,2ce496b9f80eb9fa
appnexus.com,2928,DIRECT
appnexus.com,8233,DIRECT
contextweb.com,560520,RESELLER
google.com,pub-9115524111147081,RESELLER,f08c47fec0942fa0
google.com,pub-4673227357197067,RESELLER,f08c47fec0942fa0
indexexchange.com,179394,RESELLER
lijit.com,249425,RESELLER
mobfox.com,74240,RESELLER
mobfox.com,45499,RESELLER
openx.com,539625136,RESELLER
pubmatic.com,81564,DIRECT,5d62403b186f2ace
pubmatic.com,156538,DIRECT,5d62403b186f2ace
rubiconproject.com,13510,DIRECT
smaato.com,1100037086,RESELLER
smaato.com,1100000579,RESELLER
smartadserver.com,2640,RESELLER
smartadserver.com,2441,RESELLER
sovrn.com,249425,RESELLER
spotx.tv,173175,DIRECT
spotx.tv,173177,DIRECT
spotxchange.com,173177,DIRECT
spotxchange.com,173175,DIRECT
yahoo.com,57857,RESELLER,e1a5b5b6e3255540
smartadserver.com,2161,DIRECT
pubmatic.com,156439,RESELLER,5d62403b186f2ace
pubmatic.com,154037,RESELLER,5d62403b186f2ace
rhythmone.com,2564526802,RESELLER,a670c89d4a324e47
adyoulike.com,b4bf4fdd9b0b915f746f6747ff432bde,RESELLER
smartadserver.com,3668,DIRECT
rubiconproject.com,18194,DIRECT,0bfd66d529a55807
spotx.tv,202009,DIRECT,7842df1d2fe2db34
spotxchange.com,202009,RESELLER,7842df1d2fe2db34
yieldlab.net,6378054,DIRECT
freewheel.tv,1076049,DIRECT
freewheel.tv,1076065,RESELLER
appnexus.com,8833,DIRECT,f5ab79cb980f11d1
appnexus.com,8833,RESELLER,f5ab79cb980f11d1
freewheel.tv,228,RESELLER
smartstream.tv,6459,RESELLER
appnexus.com,3368,RESELLER
yieldlab.net,2172218,RESELLER
google.com,pub-9829476400767085,DIRECT,f08c47fec0942fa0
freewheel.tv,1131585,RESELLER
piximedia.com,21168,DIRECT
adtech.com,4803,RESELLER
freewheel.tv,282482,RESELLER
freewheel.tv,283026,RESELLER
pubmatic.com,156492,RESELLER,5d62403b186f2ace
smartadserver.com,3347,DIRECT
pubmatic.com,156030,RESELLER,5d62403b186f2ace
rubiconproject.com,13132,RESELLER,0bfd66d529a55807
groundtruth.com,107,RESELLER,81cbf0a75a5e0e9a
appnexus.com,2579,DIRECT
appnexus.com,884,DIRECT
improvedigital.com,1220,DIRECT
google.com,pub-1313834454494130,RESELLER,f08c47fec0942fa0
google.com,pub-8536066741654249,RESELLER,f08c47fec0942fa0
triplelift.com,4338,DIRECT,6c33edb13117fd86
appnexus.com,1314,RESELLER
adform.com,2623,DIRECT,9f5210a2f0999e32
nobid.io,21968366300,DIRECT
google.com,pub-1051504991213440,DIRECT,f08c47fec0942fa0
google.com,pub-1835489473992347,DIRECT,f08c47fec0942fa0
google.com,pub-1789253751882305,DIRECT,f08c47fec0942fa0
google.com,pub-1950215063958302,DIRECT,f08c47fec0942fa0
appnexus.com,11429,DIRECT
gumgum.com,13926,DIRECT,ffdef49475d318a9
33across.com,0010b00002Mq2FYAAZ,DIRECT,bbea06d9c4d2853c
sovrn.com,273657,DIRECT,fafdf38b16bf6b2b
lijit.com,273657,DIRECT,fafdf38b16bf6b2b
lijit.com,273657-eb,DIRECT,fafdf38b16bf6b2b
revcontent.com,124709,DIRECT
appnexus.com,7666,RESELLER,f5ab79cb980f11d1
rubiconproject.com,156042,RESELLER,0bfd66d529a55807
my6sense.com,9732,RESELLER
criteo.com,7822,RESELLER
pubmatic.com,156423,RESELLER,5d62403b186f2ace
appnexus.com,1001,RESELLER,f5ab79cb980f11d1
appnexus.com,3135,RESELLER,f5ab79cb980f11d1
openx.com,537120563,RESELLER,6a698e2ec38604c6
openx.com,539392223,RESELLER,6a698e2ec38604c6
rhythmone.com,2439829435,RESELLER,a670c89d4a324e47
emxdgt.com,326,RESELLER,1e1d41537f7cad7f
gumgum.com,13318,RESELLER,ffdef49475d318a9
google.com,pub-9557089510405422,RESELLER,f08c47fec0942fa0
adtech.com,9993,RESELLER
adtech.com,12094,RESELLER
advangelists.com,8d3bba7425e7c98c50f52ca1b52d3735,RESELLER,60d26397ec060f98
rubiconproject.com,13702,DIRECT
pubmatic.com,157898,DIRECT,5d62403b186f2ace
adtech.com,10109,DIRECT
aolcloud.net,10109,DIRECT
openx.com,540650310,DIRECT,6a698e2ec38604c6
sonobi.com,bc2afab5f7,DIRECT,d1a215d9eb5aee9e
appnexus.com,9538,DIRECT
triplelift.com,9789,DIRECT,6c33edb13117fd86
pubmatic.com,159302,DIRECT,5d62403b186f2ace
decenterads.com,933,DIRECT
onetag.com,694e68b73971b58,DIRECT
sonobi.com,7ad1b9f952,RESELLER,d1a215d9eb5aee9e
nativo.com,5677,DIRECT
google.com,pub-1835489473992347,RESELLER,f08c47fec0942fa0
durationmedia.net,21968366300,DIRECT
yahoo.com,57872,DIRECT
smartadserver.com,3447,DIRECT
xandr.com,11429,RESELLER,f5ab79cb980f11d1
xandr.com,12701,RESELLER,f5ab79cb980f11d1
rubiconproject.com,13702,DIRECT,0bfd66d529a55807
video.unrulymedia.com,3736557092,RESELLER
rhythmone.com,3736557092,RESELLER,a670c89d4a324e47
admanmedia.com,812,DIRECT
rhythmone.com,1059622079,RESELLER,a670c89d4a324e47
contextweb.com,560606,RESELLER,89ff185a4c4e857c
amxrtb.com,105199579,DIRECT
appnexus.com,12290,RESELLER,f5ab79cb980f11d1
indexexchange.com,191503,RESELLER,50b1c356f2c5c8fc
pubmatic.com,158355,RESELLER,5d62403b186f2ace
indexexchange.com,195491,RESELLER,50b1c356f2c5c8fc
opera.com,pub5688296365760,DIRECT,55a0c5fd61378de3
indexexchange.com,192806,RESELLER,50b1c356f2c5c8fc
Pubmatic.com,158565,RESELLER,5d62403b186f2ace
smaato.com,1100042823,DIRECT,07bcf65f187117b4
rubiconproject.com,17608,RESELLER,0bfd66d529a55807
triplelift.com,10522,RESELLER,6c33edb13117fd86
smartadserver.com,4140,RESELLER
appnexus.com,2081,RESELLER,f5ab79cb980f11d1
admixer.net,5e14a984-b5c9-4ffb-87e9-d8edba8492d3,DIRECT
sovrn.com,268876,RESELLER,fafdf38b16bf6b2b
lijit.com,268876,RESELLER,fafdf38b16bf6b2b
openx.com,541031350,RESELLER,6a698e2ec38604c6
improvedigital.com,1556,RESELLER
axonix.com,56222,RESELLER
Contextweb.com,562309,RESELLER,89ff185a4c4e857c
conversantmedia.com,100066,RESELLER,03113cd04947736d
rubiconproject.com,12186,RESELLER,0bfd66d529a55807
onetag.com,72686cdf31f128b,RESELLER
lemmatechnologies.com,552,RESELLER,7829010c5bebd1fb
lemmatechnologies.com,144,RESELLER,7829010c5bebd1fb
altitude-arena.com,FIRD0F0P6T2MLDMG7GCJFTBAI8,RESELLER
leanback.digital,ESS-D666,RESELLER,b1d30350acaf0176
pubmatic.com,156494,RESELLER,5d62403b186f2ace
smartadserver.com,3564,RESELLER
admatic.com.tr,adm-pub-185375301865,RESELLER
improvedigital.com,912,RESELLER
pubmatic.com,159078,RESELLER,5d62403b186f2ace
adform.com,2600,RESELLER
stroeer.com,17938,RESELLER
sovrn.com,380632,RESELLER,fafdf38b16bf6b2b
lijit.com,380632,RESELLER,fafdf38b16bf6b2b
lijit.com,380632-eb,DIRECT,fafdf38b16bf6b2b
uis.mobfox.com,1424,RESELLER,5529a3d1f59865be
openx.com,539249210,RESELLER,6a698e2ec38604c6
impactify.io,1146,DIRECT
improvedigital.com,1058,RESELLER
google.com,pub-1343218370015870,RESELLER,f08c47fec0942fa0
google.com,pub-4301669675472368,RESELLER,f08c47fec0942fa0
spotxchange.com,176703,RESELLER,7842df1d2fe2db34
spotx.tv,176703,RESELLER,7842df1d2fe2db34
appnexus.com,11197,RESELLER,f5ab79cb980f11d1
freewheel.tv,282594,RESELLER
freewheel.tv,282786,RESELLER
freewheel.tv,282802,RESELLER
freewheel.tv,282818,RESELLER
freewheel.tv,282850,RESELLER
yahoo.com,1761548,RESELLER
rubiconproject.com,19688,RESELLER,0bfd66d529a55807
advertising.com,9516,RESELLER
smartadserver.com,2974,RESELLER
google.com,pub-7019376976432612,RESELLER
google.com,pub-5373693997956134,RESELLER,f08c47fec0942fa0
google.com,pub-4177862836555934,RESELLER,f08c47fec0942fa0
google.com,pub-1071602463683652,RESELLER,f08c47fec0942fa0
connectad.io,147,DIRECT
pubmatic.com,55990,RESELLER,5d62403b186f2ace
indexexchange.com,190906,DIRECT,50b1c356f2c5c8fc
appnexus.com,8738,RESELLER,f5ab79cb980f11d1
EMXDGT.com,1138,DIRECT,1e1d41537f7cad7f
sovrn.com,244287,DIRECT,fafdf38b16bf6b2b
lijit.com,244287,DIRECT,fafdf38b16bf6b2b
lijit.com,244287-eb,DIRECT,fafdf38b16bf6b2b
yahoo.com,55248,DIRECT
rubiconproject.com,17250,RESELLER,0bfd66d529a55807
xad.com,240,RESELLER,81cbf0a75a5e0e9a
onetag.com,5d4e109247a89f6,DIRECT
RTBHOUSE.COM,ofNe4Md3yOLt0qckkfER,DIRECT
adpone.com,59e252f6de67f6c8d1f8,DIRECT
connectad.io,50,DIRECT,85ac85a30c93b3e5
indexexchange.com,196713,DIRECT
criteo.com,B-060278,DIRECT,9fac4a4a87c2a44f
richaudience.com,06ehcbcfzk,DIRECT
betweendigital.com,42666,DIRECT
adform.com,2474,DIRECT,9f5210a2f0999e32
lijit.com,257429,RESELLER,fafdf38b16bf6b2b
sovrn.com,257429,RESELLER,fafdf38b16bf6b2b
openx.com,540603695,RESELLER,6a698e2ec38604c6
openx.com,539966405,DIRECT,6a698e2ec38604c6
pubmatic.com,157841,RESELLER,5d62403b186f2ace
pubmatic.com,156383,RESELLER,5d62403b186f2ace
smartadserver.com,1743,RESELLER,060d053dcf45cbf3
indexexchange.com,192450,DIRECT,50b1c356f2c5c8fc
appnexus.com,10264,RESELLER,f5ab79cb980f11d1
appnexus.com,10264,DIRECT,f5ab79cb980f11d1
rubiconproject.com,20266,RESELLER,0bfd66d529a55807
rubiconproject.com,17210,RESELLER,0bfd66d529a55807
google.com,pub-2128757167812663,RESELLER,f08c47fec0942fa0
adtelligent.com,315476,DIRECT
33across.com,0010b00002T3JniAAF,RESELLER,bbea06d9c4d2853c
bidtellect.com,1407,RESELLER,1c34aa2d85d45e93
contextweb.com,558355,RESELLER
EMXDGT.com,1284,RESELLER,1e1d41537f7cad7f
gumgum.com,13579,RESELLER,ffdef49475d318a9
improvedigital.com,1628,RESELLER
lijit.com,310770,RESELLER,fafdf38b16bf6b2b
onetag.com,59a18369e249bfb,RESELLER
openx.com,541177116,RESELLER,6a698e2ec38604c6
pubmatic.com,157897,RESELLER,5d62403b186f2ace
rhythmone.com,78519861,RESELLER,a670c89d4a324e47
sovrn.com,310770,RESELLER,fafdf38b16bf6b2b
synacor.com,82151,RESELLER,e108f11b2cdf7d5b
adform.com,2600,DIRECT
admatic.com.tr,adm-pub-185375301865,DIRECT
adyoulike.com,438e40b69c9e19f81b51401dce6e8be4,DIRECT,4ad745ead2958bf7
appnexus.com,11924,RESELLER,f5ab79cb980f11d1
appnexus.com,9733,RESELLER,f5ab79cb980f11d1
contextweb.com,558355,RESELLER,89ff185a4c4e857c
e-planning.net,835fbafe26d231b1,DIRECT,c1ba615865ed87b2
gumgum.com,13579,DIRECT,ffdef49475d318a9
indexexchange.com,189529,DIRECT,50b1c356f2c5c8fc
indexexchange.com,191973,RESELLER,50b1c356f2c5c8fc
lijit.com,310770,DIRECT,fafdf38b16bf6b2b
loopme.com,11378,RESELLER,6c8d5f95897a5a3b
onetag.com,59a18369e249bfb,DIRECT
pubmatic.com,156631,RESELLER,5d62403b186f2ace
pubmatic.com,156813,DIRECT,5d62403b186f2ace
pubmatic.com,159078,DIRECT,5d62403b186f2ace
rhythmone.com,1767353092,RESELLER,a670c89d4a324e47
rubiconproject.com,12398,RESELLER,0bfd66d529a55807
rubiconproject.com,17184,DIRECT,0bfd66d529a55807
rubiconproject.com,21642,RESELLER,0bfd66d529a55807
sovrn.com,310770,DIRECT,fafdf38b16bf6b2b
spotim.market,4446666,DIRECT,077e5f709d15bdbb
stroeer.com,17938,DIRECT
152media.info,152M10,RESELLER
rhythmone.com,3139274702404301777,DIRECT,a670c89d4a324e47
video.unrulymedia.com,3139274702404301777,DIRECT
indexexchange.com,182257,RESELLER,50b1c356f2c5c8fc
appnexus.com,6849,RESELLER,f5ab79cb980f11d1
rubiconproject.com,15268,RESELLER,0bfd66d529a55807
pubmatic.com,159277,RESELLER,5d62403b186f2ace
advertising.com,28605,RESELLER
openx.com,543878511,RESELLER,6a698e2ec38604c6
improvedigital.com,1699,RESELLER
pubmatic.com,161562,RESELLER,5d62403b186f2ace
vidoomy.com,2252369,DIRECT
Qwarry.com,12,DIRECT,bf16059e4b3fb977
themediagrid.com,IH9PA4,DIRECT,35d5010d7789b49d
criteo.com,B-059164,DIRECT,9fac4a4a87c2a44f
themediagrid.com,7WYFHG,DIRECT,35d5010d7789b49d
amxrtb.com,105199542,DIRECT
appnexus.com,11786,RESELLER,f5ab79cb980f11d1
lijit.com,260380,RESELLER,fafdf38b16bf6b2b
sovrn.com,260380,RESELLER,fafdf38b16bf6b2b
appnexus.com,9393,RESELLER,f5ab79cb980f11d1
advertising.com,28305,RESELLER
adform.com,2865,RESELLER
smartadserver.com,3056,DIRECT
viralize.com,4720,DIRECT
adform.com,2688,RESELLER,9f5210a2f0999e32
adform.com,2437,RESELLER,9f5210a2f0999e32
freewheel.tv,1003361,DIRECT
freewheel.tv,1003377,RESELLER
freewheel.tv,939745,DIRECT
freewheel.tv,941377,RESELLER
pubmatic.com,156695,DIRECT,5d62403b186f2ace
pubmatic.com,160405,RESELLER,5d62403b186f2ace
improvedigital.com,1227,RESELLER
spotxchange.com,241914,RESELLER,7842df1d2fe2db34
spotx.tv,241914,RESELLER,7842df1d2fe2db34
conversantmedia.com,100098,RESELLER,03113cd04947736d
appnexus.com,4052,RESELLER
contextweb.com,561998,RESELLER,89ff185a4c4e857c
openx.com,540031703,RESELLER,6a698e2ec38604c6
pubmatic.com,158100,RESELLER,5d62403b186f2ace
yahoo.com,55771,RESELLER,e1a5b5b6e3255540
loopme.com,11230,RESELLER,6c8d5f95897a5a3b
freewheel.tv,1137761,RESELLER
freewheel.tv,1138529,RESELLER
freewheel.tv,962145,RESELLER
freewheel.tv,962209,RESELLER
improvedigital.com,1175,RESELLER
freewheel.tv,1174465,RESELLER
freewheel.tv,1174481,RESELLER
undertone.com,3393,RESELLER
appnexus.com,2234,RESELLER
openx.com,537153564,RESELLER,6a698e2ec38604c6
ogury.com,f00b15ea-6210-4e34-bb76-384d7003d8e8,DIRECT
appnexus.com,11470,RESELLER
avantisvideo.com,8798,DIRECT
Advertising.com,23598,DIRECT
advertising.com,28918,DIRECT
Appnexus.com,10062,DIRECT,f5ab79cb980f11d1
EMXDGT.com,1745,DIRECT,1e1d41537f7cad7f
google.com,pub-2024690810381654,RESELLER,f08c47fec0942fa0
indexexchange.com,192106,DIRECT
indexexchange.com,193375,RESELLER
Pubmatic.com,159970,RESELLER,5d62403b186f2ace
Pubmatic.com,160454,RESELLER,5d62403b186f2ace
Pubmatic.com,160265,RESELLER,5d62403b186f2ace
Contextweb.com,562357,DIRECT,89ff185a4c4e857c
spotxchange.com,165877,RESELLER,7842df1d2fe2db34
spotx.tv,165877,RESELLER,7842df1d2fe2db34
rhythmone.com,871930104,DIRECT,a670c89d4a324e47
video.unrulymedia.com,871930104,DIRECT
google.com,pub-5717092533913515,RESELLER,f08c47fec0942fa0
indexexchange.com,185192,DIRECT
rhythmone.com,1149317856,DIRECT,a670c89d4a324e47
rubiconproject.com,17346,DIRECT,0bfd66d529a55807
pubmatic.com,157904,DIRECT,5d62403b186f2ace
sharethrough.com,8a03a67b,DIRECT,d53b998a7bd4ecd2
indexexchange.com,186046,RESELLER,50b1c356f2c5c8fc
spotxchange.com,212457,RESELLER
spotx.tv,212457,RESELLER,7842df1d2fe2db34
pubmatic.com,156557,RESELLER
pubmatic.com,158723,RESELLER,5d62403b186f2ace
rubiconproject.com,18694,RESELLER,0bfd66d529a55807
openx.com,540274407,RESELLER,6a698e2ec38604c6
33across.com,0013300001kQj2HAAS,RESELLER,bbea06d9c4d2853c
smaato.com,1100047713,RESELLER,07bcf65f187117b4
appnexus.com,9027,DIRECT
aax.media,AAX23QE99,DIRECT
Media.net,8CUOMF1PP,DIRECT
pubmatic.com,158984,RESELLER,5d62403b186f2ace
openx.com,543731411,RESELLER,6a698e2ec38604c6
indexexchange.com,192393,RESELLER
districtm.io,100600,RESELLER
sonobi.com,83729e979b,RESELLER
onetag.com,66d66dec41ef0cc,RESELLER
appnexus.com,10273,RESELLER,f5ab79cb980f11d1
indexexchange.com,192922,RESELLER,50b1c356f2c5c8fc
onetag.com,5adb88524e24e50,RESELLER
engagebdr.com,10427,RESELLER
google.com,pub-9945624415527048,DIRECT,f08c47fec0942fa0
Media.net,8PR6YK195,DIRECT
EMXDGT.com,1759,RESELLER,1e1d41537f7cad7f
google.com,pub-7310785613215102,DIRECT,f08c47fec0942fa0
google.com,pub-8600492219386651,DIRECT,f08c47fec0942fa0
e-planning.net,d6e04fe7533a7d3b,DIRECT,c1ba615865ed87b2
indexexchange.com,190243,DIRECT
richaudience.com,25BiP9IMgN,DIRECT
aol.com,57992,RESELLER,e1a5b5b6e3255540
Yahoo.com,57992,RESELLER,e1a5b5b6e3255540
sonobi.com,8efb591506,DIRECT,d1a215d9eb5aee9e
sonobi.com,4d443a3ea2,RESELLER,d1a215d9eb5aee9e
adriver.ru,187150,DIRECT
smartadserver.com,2491,RESELLER
advertising.com,21483,DIRECT,e1a5b5b6e3255540
improvedigital.com,1010,RESELLER
indexexchange.com,193216,RESELLER
admanmedia.com,722,DIRECT
video.unrulymedia.com,3948367200,RESELLER
rhythmone.com,3948367200,RESELLER,a670c89d4a324e47
appnexus.com,8804,RESELLER,f5ab79cb980f11d1
smartadserver.com,3713,RESELLER
improvedigital.com,1668,RESELLER
indexexchange.com,191497,RESELLER
openx.com,540866936,RESELLER,6a698e2ec38604c6
appnexus.com,10040,RESELLER
rubiconproject.com,19814,RESELLER,0bfd66d529a55807
spotxchange.com,178357,RESELLER,7842df1d2fe2db34
spotx.tv,178357,RESELLER,7842df1d2fe2db34
pubmatic.com,158810,RESELLER,5d62403b186f2ace
pubmatic.com,158481,DIRECT,5d62403b186f2ace
spotx.tv,238936,RESELLER,7842df1d2fe2db34
rubiconproject.com,19668,RESELLER,0bfd66d529a55807
indexexchange.com,190856,RESELLER,50b1c356f2c5c8fc
pubmatic.com,158615,RESELLER,5d62403b186f2ace
indexexchange.com,183965,RESELLER,50b1c356f2c5c8fc
pubmatic.com,156458,RESELLER,5d62403b186f2ace
pubmatic.com,156325,RESELLER,5d62403b186f2ace
pubmatic.com,156674,RESELLER,5d62403b186f2ace
rubiconproject.com,18222,RESELLER,0bfd66d529a55807
rubiconproject.com,16114,DIRECT
azeriondigital.com,43710415,DIRECT
appnexus.com,12223,RESELLER,f5ab79cb980f11d1
improvedigital.com,1210,RESELLER
improvedigital.com,1221,RESELLER
pubmatic.com,150561,RESELLER,5d62403b186f2ace
EMXDGT.com,1836,DIRECT,1e1d41537f7cad7f
EMXDGT.com,1289,DIRECT,1e1d41537f7cad7f
advertising.com,28335,DIRECT,e1a5b5b6e3255540
smilewanted.com,1362,DIRECT
adyoulike.com,b3e21aeb2e950aa59e5e8cc1b6dd6f8e,DIRECT,4ad745ead2958bf7
loopme.com,11013,DIRECT,6c8d5f95897a5a3b
connectad.io,204,DIRECT,85ac85a30c93b3e5
EMXDGT.com,1701,DIRECT,1e1d41537f7cad7f
quantum-advertising.com,6222,RESELLER
themediagrid.com,BG415O,DIRECT,35d5010d7789b49d
smartadserver.com,3392,DIRECT
appnexus.com,10212,RESELLER
improvedigital.com,1633,RESELLER
yahoo.com,58977,RESELLER,e1a5b5b6e3255540
onetag.com,75779831fd8c740,DIRECT
adyoulike.com,22e5955a10a7f98b037f13dd297cdd74,DIRECT,4ad745ead2958bf7
freewheel.tv,1089937,DIRECT
freewheel.tv,1099761,RESELLER
bliink.io,cfe6f06e-2ff0-11eb-8d68-7aaa96b266b5,DIRECT
gothamads.com,1750,DIRECT,d9c86e5dec870222
connectad.io,190,DIRECT,85ac85a30c93b3e5
improvedigital.com,1937,RESELLER
e-planning.net,54275499d4eb431b,DIRECT,c1ba615865ed87b2
trmqb.com,4512,DIRECT
ssp.logan.ai,LG9,RESELLER
opera.com,pub6060502141568,DIRECT,55a0c5fd61378de3
openx.com,544015448,RESELLER,6a698e2ec38604c6
synacor.com,82460,DIRECT,e108f11b2cdf7d5b
video.unrulymedia.com,123476257,RESELLER
bizzclick.com,30,RESELLER,7e936b1feafdaa61
betweendigital.com,43818,RESELLER
smaato.com,1100042823,RESELLER,07bcf65f187117b4
mobilefuse.com,3719,RESELLER,71e88b065d69c021
conversantmedia.com,100269,RESELLER,03113cd04947736d
outbrain.com,002d7f7ba0bd74452f2b155d0dfb5cd6c8,RESELLER
yahoo.com,58935,RESELLER,e1a5b5b6e3255540
inmobi.com,f58140d7af1a4fcb83deb5b1c76f0c04,RESELLER,83e75a7ae333ca9d
tpmn.io,472,RESELLER
seedtag.com,619f620afe426c0700a5c30d,DIRECT
seedtag.com,61a78375e0fb8f0800ec50fb,DIRECT
seedtag.com,61a783c8517244070096f118,DIRECT
seedtag.com,61a783f0e0fb8f0800ec50fc,DIRECT
seedtag.com,61a7804cfe829e0700f0db81,DIRECT
seedtag.com,61a7849ac342880700fc6da2,DIRECT
seedtag.com,61a784f8fe829e0700f0dbba,DIRECT
seedtag.com,61a78466517244070096f119,DIRECT
seedtag.com,61a78446c342880700fc6da1,DIRECT
pubmatic.com,157743,DIRECT,5d62403b186f2ace
spotxchange.com,249286,DIRECT,7842df1d2fe2db34
spotx.tv,249286,DIRECT,7842df1d2fe2db34
rubiconproject.com,17280,DIRECT,0bfd66d529a55807
33across.com,0010b00002MptHCAAZ,DIRECT,bbea06d9c4d2853c
indexexchange.com,191730,RESELLER
improvedigital.com,1680,RESELLER
smartadserver.com,3050,DIRECT
contextweb.com,560288,DIRECT,89ff185a4c4e857c
openx.com,537149888,DIRECT,6a698e2ec38604c6
districtm.io,101760,DIRECT,3fd707be9c4527c3
xandr.com,4009,DIRECT
richaudience.com,ns9qrKJLKD,DIRECT
aerserv.com,2750,DIRECT,2ce496b9f80eb9fa
aolcloud.net,4687,DIRECT
mobfox.com,74240,DIRECT
openx.com,539625136,DIRECT
smaato.com,1100037086,DIRECT
adyoulike.com,83d15ef72d387a1e60e5a1399a2b0c03,DIRECT
yahoo.com,58578,DIRECT,e1a5b5b6e3255540
aol.com,58578,DIRECT,e1a5b5b6e3255540
advertising.com,29034,DIRECT
adform.com,1889,RESELLER,9f5210a2f0999e32
condigolabs.com,c6blkn6kv5dumh3tsfj0,RESELLER
33across.com,0015a00002vNEdMAAW,DIRECT,bbea06d9c4d2853c
conversantmedia.com,100141,DIRECT
gumgum.com,15500,RESELLER,ffdef49475d318a9
justpremium.com,2976,RESELLER
appnexus.com,2758,RESELLER,f5ab79cb980f11d1
rubiconproject.com,23434,RESELLER,0bfd66d529a55807
openx.com,537149485,RESELLER,6a698e2ec38604c6
admanmedia.com,799,RESELLER
smartadserver.com,4005,RESELLER
33across.com,0013300001r0t9mAAA,RESELLER,bbea06d9c4d2853c
vidoomy.com,62496,DIRECT
google.com,pub-2831120411392012,RESELLER,f08c47fec0942fa0
tremorhub.com,4cywq-a04wk,RESELLER,1a4e959a1b50034a
yieldmo.com,2731991718797714293,DIRECT
adform.com,2742,RESELLER
advertising.com,22762,RESELLER
aol.com,22762,RESELLER
adtech.com,11303,RESELLER
advertising.com,26631,RESELLER
appnexus.com,12475,RESELLER,f5ab79cb980f11d1
pubmatic.com,156498,RESELLER,5d62403b186f2ace
freewheel.tv,872257,RESELLER
freewheel.tv,894193,RESELLER
openx.com,540804929,RESELLER,6a698e2ec38604c6
lkqd.net,430,RESELLER,59c49fa9598a0117
lkqd.com,430,RESELLER,59c49fa9598a0117
districtm.io,101540,RESELLER,3fd707be9c4527c3
spotxchange.com,218443,RESELLER,7842df1d2fe2db34
spotx.tv,218443,RESELLER,7842df1d2fe2db34
emxdgt.com,1495,RESELLER,1e1d41537f7cad7f
beachfront.com,6547,RESELLER
smartadserver.com,3136,RESELLER
smartadserver.com,1963,RESELLER
smartadserver.com,3276,RESELLER
improvedigital.com,1738,RESELLER
conversantmedia.com,100112,DIRECT,03113cd04947736d
appnexus.com,4052,RESELLER,f5ab79cb980f11d1
aol.com,55011,RESELLER,e1a5b5b6e3255540
indexexchange.com,192311,RESELLER
indexexchange.com,193069,RESELLER
loopme.com,11058,RESELLER,6c8d5f95897a5a3b
google.com,pub-7995104076770938,DIRECT,f08c47fec0942fa0
appnexus.com,8790,RESELLER,f5ab79cb980f11d1
indexexchange.com,187924,DIRECT
indexexchange.com,189458,DIRECT
openx.com,540322758,RESELLER,6a698e2ec38604c6
pubmatic.com,157102,RESELLER,5d62403b186f2ace
pubmatic.com,157163,RESELLER,5d62403b186f2ace
pubmatic.com,157752,RESELLER,5d62403b186f2ace
rubiconproject.com,13894,RESELLER,0bfd66d529a55807
rubiconproject.com,18008,RESELLER,0bfd66d529a55807
yahoo.com,56860,RESELLER,e1a5b5b6e3255540
aol.com,56860,RESELLER,e1a5b5b6e3255540
rhythmone.com,274200170,RESELLER,a670c89d4a324e47
video.unrulymedia.com,274200170,RESELLER,a670c89d4a324e47
yahoo.com,59652,RESELLER,e1a5b5b6e3255540
appnexus.com,1868,RESELLER
appnexus.com,11664,RESELLER
EMXDGT.com,273,RESELLER,1e1d41537f7cad7f
indexexchange.com,184110,RESELLER,50b1c356f2c5c8fc
indexexchange.com,184349,RESELLER,50b1c356f2c5c8fc
indexexchange.com,195924,DIRECT
indexexchange.com,183875,RESELLER,50b1c356f2c5c8fc
indexexchange.com,184626,RESELLER,50b1c356f2c5c8fc
openx.com,544096208,RESELLER,6a698e2ec38604c6
pubmatic.com,156971,RESELLER,5d62403b186f2ace
pubmatic.com,133799,RESELLER,5d62403b186f2ace
pubmatic.com,156078,RESELLER,5d62403b186f2ace
pubmatic.com,157840,RESELLER,5d62403b186f2ace
pubmatic.com,155967,RESELLER,5d62403b186f2ace
pubmatic.com,160048,RESELLER,5d62403b186f2ace
pubmatic.com,156084,RESELLER,5d62403b186f2ace
contextweb.com,562258,RESELLER,89ff185a4c4e857c
telaria.com,4jdlm-4qsx6,RESELLER,1a4e959a1b50034a
tremorhub.com,4jdlm-4qsx6,RESELLER,1a4e959a1b50034a
triplelift.com,9979,RESELLER,6c33edb13117fd86
media.net,8CUIHQJ4B,RESELLER
indexexchange.com,196845,RESELLER,50b1c356f2c5c8fc
sovrn.com,378732,RESELLER,fafdf38b16bf6b2b
lijit.com,378732,RESELLER,fafdf38b16bf6b2b
33across.com,0010b00002EdWnZAAV,RESELLER,bbea06d9c4d2853c
pubmatic.com,161784,RESELLER,5d62403b186f2ace
pubmatic.com,161593,RESELLER,5d62403b186f2ace
improvedigital.com,1790,RESELLER
smartadserver.com,3554,RESELLER
33across.com,0015a00002oUk4aAAC,RESELLER,bbea06d9c4d2853c
richaudience.com,1BTOoaD22a,RESELLER
pubmatic.com,81564,RESELLER,5d62403b186f2ace
rubiconproject.com,13510,RESELLER
yahoo.com,49648,RESELLER
rubiconproject.com,24298,RESELLER,0bfd66d529a55807
inmobi.com,8f261ace12c3486ba2e0d2011cd97976,DIRECT,83e75a7ae333ca9d
adform.com,2736,RESELLER,9f5210a2f0999e32
pubmatic.com,160987,RESELLER,5d62403b186f2ace
pubmatic.com,160998,RESELLER,5d62403b186f2ace
google.com,pub-7019376976432612,RESELLER,f08c47fec0942fa0
yahoo.com,59133,RESELLER,e1a5b5b6e3255540
yahoo.com,59356,RESELLER,e1a5b5b6e3255540
EMXDGT.com,1966,RESELLER,1e1d41537f7cad7f
smartadserver.com,3056,RESELLER
pubmatic.com,161527,RESELLER,5d62403b186f2ace
rubiconproject.com,23844,DIRECT,0bfd66d529a55807
yahoo.com,59531,RESELLER,e1a5b5b6e3255540
smartadserver.com,4071,RESELLER
152media.info,152M1,RESELLER
indexexchange.com,189372,RESELLER,50b1c356f2c5c8fc
consumable.com,2001326,RESELLER,aefcd3d2f45b5070
Media.net,8PR6YK195,RESELLER
rubiconproject.com,23280,RESELLER,0bfd66d529a55807
smartadserver.com,4102,RESELLER
vidoomy.com,57205,RESELLER
EMXDGT.com,2007,DIRECT,1e1d41537f7cad7f
uis.mobfox.com,1263,RESELLER,5529a3d1f59865be
loopme.com,11470,RESELLER,6c8d5f95897a5a3b
onetag.com,5927d926323dc2c,DIRECT
yandex.com,97790217,DIRECT
openx.com,557083110,RESELLER,6a698e2ec38604c6
yahoo.com,59702,DIRECT,e1a5b5b6e3255540
loopme.com,11468,RESELLER,6c8d5f95897a5a3b
contextweb.com,562499,RESELLER,89ff185a4c4e857c
indexexchange.com,194730,RESELLER
outbrain.com,00fe7cdd9f63b40ea93c0c4ae346bf4541,DIRECT
vi.ai,987349031605160,DIRECT
xandr.com,10736,RESELLER
freewheel.tv,1220655,RESELLER
indexexchange.com,193091,RESELLER,50b1c356f2c5c8fc
improvedigital.com,1863,RESELLER
loopme.com,11314,RESELLER,6c8d5f95897a5a3b
triplelift.com,11656,RESELLER,6c33edb13117fd86
appnexus.com,13227,RESELLER
yandex.com,95746987,RESELLER
rubiconproject.com,24386,RESELLER,0bfd66d529a55807
### THE MONEYTIZER END ###
### Sovrn ###
sovrn.com, 306258, DIRECT, fafdf38b16bf6b2b
lijit.com, 306258, DIRECT, fafdf38b16bf6b2b
lijit.com, 306258-eb, DIRECT, fafdf38b16bf6b2b
### Sovrn END ###
### Revcontent ###
revcontent.com, 92656, DIRECT
engagebdr.com, 10304, RESELLER
synacor.com, 82291, RESELLER, e108f11b2cdf7d5b
indexexchange.com, 192143, RESELLER, 50b1c356f2c5c8fc
### Revcontent END ###
### 33Across ###
33across.com, 0010b00002cnuc6AAA, DIRECT, bbea06d9c4d2853c
rubiconproject.com, 21642, RESELLER, 0bfd66d529a55807
rubiconproject.com, 21434, RESELLER, 0bfd66d529a55807
rubiconproject.com, 21720, RESELLER, 0bfd66d529a55807
pubmatic.com, 158569, RESELLER, 5d62403b186f2ace
openx.com, 540995201, RESELLER, 6a698e2ec38604c6
aol.com, 47594, RESELLER, e1a5b5b6e3255540
yahoo.com,
google.com, pub-8787923930478618, RESELLER, f08c47fec0942fa0
yahoo.com,
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